Evaluation of techniques for increasing recall in a dictionary approach to gene and protein name identification.

@article{citeulike:2412875, abstract = {Gene and protein name identification in text requires a dictionary approach to relate synonyms to the same gene or protein, and to link names to external databases. However, existing dictionaries are incomplete. We investigate two complementary methods for automatic generation of a comprehensive dictionary: combination of information from existing gene and protein databases and rule-based generation of spelling variations. Both methods have been reported in literature before, but have hitherto not been combined and evaluated systematically. We combined gene and protein names from several existing databases of four different organisms. The combined dictionaries showed a substantial increase in recall on three different test sets, as compared to any single database. Application of 23 spelling variation rules to the combined dictionaries further increased recall. However, many rules appeared to have no effect and some appear to have a detrimental effect on precision.}, address = {Department of Medical Informatics, Erasmus University Medical Center Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. m.schuemie@erasmusmc.nl}, author = {Schuemie, M. J. and Mons, B. and Weeber, M. and Kors, J. A. }, citeulike-article-id = {2412875}, doi = {http://dx.doi.org/10.1016/j.jbi.2006.09.002}, issn = {1532-0480}, journal = {J Biomed Inform}, keywords = {ner}, month = {June}, number = {3}, pages = {316--324}, posted-at = {2008-06-09 08:11:20}, priority = {2}, title = {Evaluation of techniques for increasing recall in a dictionary approach to gene and protein name identification.}, url = {http://dx.doi.org/10.1016/j.jbi.2006.09.002}, volume = {40}, year = {2007} }

TY - JOUR ID - citeulike:2412875 L3 - citeulike-article-id:2412875 TI - Evaluation of techniques for increasing recall in a dictionary approach to gene and protein name identification. JF - J Biomed Inform VL - 40 IS - 3 SP - 316 EP - 324 AD - Department of Medical Informatics, Erasmus University Medical Center Rotterdam, P.O. Box 1738, 3000 DR, Rotterdam, The Netherlands. m.schuemie@erasmusmc.nl SN - 1532-0480 N2 - Gene and protein name identification in text requires a dictionary approach to relate synonyms to the same gene or protein, and to link names to external databases. However, existing dictionaries are incomplete. We investigate two complementary methods for automatic generation of a comprehensive dictionary: combination of information from existing gene and protein databases and rule-based generation of spelling variations. Both methods have been reported in literature before, but have hitherto not been combined and evaluated systematically. We combined gene and protein names from several existing databases of four different organisms. The combined dictionaries showed a substantial increase in recall on three different test sets, as compared to any single database. Application of 23 spelling variation rules to the combined dictionaries further increased recall. However, many rules appeared to have no effect and some appear to have a detrimental effect on precision. KW - ner AU - Schuemie, MJ AU - Mons, B AU - Weeber, M AU - Kors, JA PY - 2007/06// UR - http://dx.doi.org/10.1016/j.jbi.2006.09.002 ER -