WebLogo: A Sequence Logo Generator

by: Gavin E Crooks, Gary Hon, John-Marc Chandonia, Steven E Brenner

Genome Res., Vol. 14, No. 6. (1 June 2004), pp. 1188-1190.

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Abstract

WebLogo generates sequence logos, graphical representations of the patterns within a multiple sequence alignment. Sequence logos provide a richer and more precise description of sequence similarity than consensus sequences and can rapidly reveal significant features of the alignment otherwise difficult to perceive. Each logo consists of stacks of letters, one stack for each position in the sequence. The overall height of each stack indicates the sequence conservation at that position (measured in bits), whereas the height of symbols within the stack reflects the relative frequency of the corresponding amino or nucleic acid at that position. WebLogo has been enhanced recently with additional features and options, to provide a convenient and highly configurable sequence logo generator. A command line interface and the complete, open WebLogo source code are available for local installation and customization.

@article{citeulike:407124, abstract = {WebLogo generates sequence logos, graphical representations of the patterns within a multiple sequence alignment. Sequence logos provide a richer and more precise description of sequence similarity than consensus sequences and can rapidly reveal significant features of the alignment otherwise difficult to perceive. Each logo consists of stacks of letters, one stack for each position in the sequence. The overall height of each stack indicates the sequence conservation at that position (measured in bits), whereas the height of symbols within the stack reflects the relative frequency of the corresponding amino or nucleic acid at that position. WebLogo has been enhanced recently with additional features and options, to provide a convenient and highly configurable sequence logo generator. A command line interface and the complete, open WebLogo source code are available for local installation and customization.}, author = {Crooks, Gavin E. and Hon, Gary and Chandonia, John-Marc and Brenner, Steven E. }, citeulike-article-id = {407124}, doi = {10.1101/gr.849004}, journal = {Genome Res.}, month = {June}, number = {6}, pages = {1188--1190}, posted-at = {2007-12-12 15:10:45}, priority = {2}, title = {WebLogo: A Sequence Logo Generator}, url = {http://dx.doi.org/10.1101/gr.849004}, volume = {14}, year = {2004} }

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TY - JOUR ID - citeulike:407124 L3 - citeulike-article-id:407124 TI - WebLogo: A Sequence Logo Generator JF - Genome Res. VL - 14 IS - 6 SP - 1188 EP - 1190 N2 - WebLogo generates sequence logos, graphical representations of the patterns within a multiple sequence alignment. Sequence logos provide a richer and more precise description of sequence similarity than consensus sequences and can rapidly reveal significant features of the alignment otherwise difficult to perceive. Each logo consists of stacks of letters, one stack for each position in the sequence. The overall height of each stack indicates the sequence conservation at that position (measured in bits), whereas the height of symbols within the stack reflects the relative frequency of the corresponding amino or nucleic acid at that position. WebLogo has been enhanced recently with additional features and options, to provide a convenient and highly configurable sequence logo generator. A command line interface and the complete, open WebLogo source code are available for local installation and customization. AU - Crooks, Gavin AU - Hon, Gary AU - Chandonia, John-Marc AU - Brenner, Steven PY - 2004/06/01/ UR - http://dx.doi.org/10.1101/gr.849004 ER -

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