The patA gene product, which contains a region similar to CheY of Escherichia coli, controls heterocyst pattern formation in the cyanobacterium Anabaena 7120.

@article{citeulike:2679220, abstract = {In Anabaena 7120, heterocysts (cells specialized for nitrogen fixation) develop at the ends of filaments and at intervals within each filament. We have isolated a mutant Anabaena strain that develops heterocysts mostly at the ends of filaments. This mutant, PAT-1, grows poorly under nitrogen-fixing conditions. The wild-type gene that complements the mutation in PAT-1, called patA, was cloned and sequenced. The predicted PatA protein contains 379 amino acids distributed among three "domains" based on predictions of hydropathy and flexibility. The carboxyl-terminal domain is very similar to that of CheY and other response regulators in two-component regulatory systems in eubacteria. The patA mutation suppresses the multiheterocyst phenotype produced by extra copies of the wild-type hetR gene described previously, suggesting that PatA and HetR are components of the same environment-sensing regulatory circuit in Anabaena.}, address = {Department of Molecular Genetics and Cell Biology, University of Chicago, IL 60637.}, author = {Liang, J. and Scappino, L. and Haselkorn, R. }, citeulike-article-id = {2679220}, doi = {http://dx.doi.org/10.1073/pnas.89.12.5655}, issn = {0027-8424}, journal = {Proceedings of the National Academy of Sciences of the United States of America}, keywords = {biochempaper, cyanobacteria, heterocyst, pata}, month = {June}, number = {12}, pages = {5655--5659}, posted-at = {2008-04-17 01:18:06}, priority = {2}, title = {The patA gene product, which contains a region similar to CheY of Escherichia coli, controls heterocyst pattern formation in the cyanobacterium Anabaena 7120.}, url = {http://dx.doi.org/10.1073/pnas.89.12.5655}, volume = {89}, year = {1992} }

TY - JOUR ID - citeulike:2679220 L3 - citeulike-article-id:2679220 TI - The patA gene product, which contains a region similar to CheY of Escherichia coli, controls heterocyst pattern formation in the cyanobacterium Anabaena 7120. JF - Proceedings of the National Academy of Sciences of the United States of America VL - 89 IS - 12 SP - 5655 EP - 5659 AD - Department of Molecular Genetics and Cell Biology, University of Chicago, IL 60637. SN - 0027-8424 N2 - In Anabaena 7120, heterocysts (cells specialized for nitrogen fixation) develop at the ends of filaments and at intervals within each filament. We have isolated a mutant Anabaena strain that develops heterocysts mostly at the ends of filaments. This mutant, PAT-1, grows poorly under nitrogen-fixing conditions. The wild-type gene that complements the mutation in PAT-1, called patA, was cloned and sequenced. The predicted PatA protein contains 379 amino acids distributed among three "domains" based on predictions of hydropathy and flexibility. The carboxyl-terminal domain is very similar to that of CheY and other response regulators in two-component regulatory systems in eubacteria. The patA mutation suppresses the multiheterocyst phenotype produced by extra copies of the wild-type hetR gene described previously, suggesting that PatA and HetR are components of the same environment-sensing regulatory circuit in Anabaena. KW - biochempaper KW - cyanobacteria KW - heterocyst KW - pata AU - Liang, J AU - Scappino, L AU - Haselkorn, R PY - 1992/06/15/ UR - http://dx.doi.org/10.1073/pnas.89.12.5655 ER -